The RowdyRuff Boys are the real enemies of The PowerPuff Girls. Unlike the girls, they are obviusly boys, but all are chipmunks like the girls.
In the TV series, the RRB were created by Mojo Jojo and were later killed by cooties but got resurrected by Him and received a vaccine against the "cooties".
Even though they are villains, they usually don't care about other villains or be friendly to them either. They had kidnapped Capone and took over his mansion, attacked the Platypus Aliens, and even put graffiti on Rabbit's garden, often flying away before Rabbit can get them. They can be distinguished by their coloured shirts and one of the boys has a red backwards cap.
- Mojo Jojo